make a difference to sb (do sth )意为对某人(做某物)有影响 make a difference in sth(doing sth )意为对某物(做某事)有影响 如:1,It makes a great differences to me.它对我有很大的影响. 2,It makes a difference to keep fit.它对保持健康有影响. 3,It makes a difference in my health.它对我的健康有影响. 4,It makes a great differentces in singing.它对唱歌有很大的影响.