1.My parents advised me to take a ____ on how to make dresse

1.My parents advised me to take a ____ on how to make dresses,in which l showed no interest at all.
A.course B.comment C.choise D.career
2.It was only after she played the leading role in a film directed by Spielberg in the 1980s that her acting career really ____.
A.took up B.took away C.took off D.took in
3.It seems that the old man over there ____ something.Let's go and see what we can do for him.
A.lose B.has lost C.had lost D.was losing
4.—You owe her an apology,l suppose.
—I ____ not apologize to her.It's not my fault,after all.
A.will B.may C.must D.could
5.I'm going to London this summer and l'll seize the opportunity to practice my spoken·English ____ l am there.
A.though B.because C.if D.while
6.With the deadline drawing near,we have to work ____ hous this week.
A.spare B.extra C.special D.normal
希望能够给我讲解!