low-penetrant什么意思?医学文献里的词组,应该是和基因有关系,

xhb521chy 1年前 已收到1个回答 举报

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就是指一个基因的的表型是否可以得到比较多的表达:low就是表达,或者该基因的影响较小.
Penetrance in genetics is the proportion of individuals carrying a particular variant of a gene (allele or genotype) that also expresses an associated trait (phenotype).In medical genetics,the penetrance of a disease-causing mutation is the proportion of individuals with the mutation who exhibit clinical symptoms.For example,if a mutation in the gene responsible for a particular autosomal dominant disorder has 95% penetrance,then 95% of those with the mutation will develop the disease,while 5% will not.

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