人生总有不如意时 There is a crook in the lot of every one [参考词典]:汉英综合大词典 人生麻烦事,接连不断来 life is one damn thing after another; life is one damned thing after another [参考词典]:汉英综合大词典 Not everything can go on as one wishes in one's whole life No perfect life shit happens 参考资料:出自《friends》